برهمکنش واکسن نیوکاسل با پاسخ سرمی ناشی از واکسن بیماری لارنگوتراکئیت عفونی پرندگان

نوع مقاله : مقاله کامل

نویسندگان

1 دانشکده دامپزشکی، دانشگاه آزاد اسلامی، واحد علوم و تحقیقات، تهران، ایران

2 گروه میکروبیولوژی و ایمنولوژی، دانشکده دامپزشکی، دانشگاه تهران. تهران. ایران

3 گروه علوم بالینی، دانشکده دامپزشکی، دانشگاه آزاد اسلامی، واحد کرج، کرج، ایران

چکیده

بیماری لارنگوتراکئیت عفونی (Infectious Laryngotrahetis) یک بیماری مهم اقتصادی دستگاه تنفس در میان ماکیان می‌باشد. این بیماری به شدت واگیردار بوده و بوسیله آلفاهرپس ویروس تیپ یک طیور (GaHV-1) ایجاد می‌شود. هدف از انجام این مطالعه بررسی اثرات واکسن نیوکاسل بر روی واکسن لارنگوتراکئیت بوده است. بر این اساس تعداد ۱۲۵ عدد پولت تخم‌گذار LSL 27 روزه را بصورت کاملا تصادفی به پنج گروه تقسیم و در اتاق‌های جداگانه در دمای استاندارد نگهداری و طبق یک برنامه خاص با واکسن نیوکاسل و لارنگوتراکئیت عفونی واکسینه گردیدند، سه هفته بعد از واکسیناسیون، سرم‌ها با استفاده از آزمون ممانعت از هماگلوتیناسیون (HI) جهت بررسی تیتر نیوکاسل و الایزا جهت بررسی تیتر لارنگوتراکئیت مورد آزمایش قرار گرفتند. نتایج این مطالعه نشان داد تیتر لارنگوتراکئیت عفونی (631±1990) در گروهی (G4) که ابتدا واکسن نیوکاسل و سه روز بعد واکسن لارنگوتراکئیت عفونی دریافت نمود، بیشتر از سایر گروه‌ها و بصورت معنی‌دار بود (05/0>P) و تیتر نیوکاسل (45/1±1/5) در این گروه بطور غیرمعنی‌داری از سایر گروه‌ها کمتر بود (05/0

کلیدواژه‌ها


عنوان مقاله [English]

Interaction of Newcastle disease vaccine on serum response induced by avian infectious laryngotracheitis vaccine

نویسندگان [English]

  • A. Arjangpour 1
  • A. Ghalyanchi Langeroudi 2
  • H. Hosseini 3
  • K. Parvandar Asadollahi 1
1 Department of Clinical Sciences, College of Veterinary Medicine, Science and Research Branch, Islamic Azad University, Tehran, Iran.
2 Department of Microbiology and Immunology, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran.
3 Department of Clinical Sciences, College of Veterinary Medicine, Karaj Branch, Islamic Azad University, Karaj, Iran.
چکیده [English]

Infectious Larangotracheitis (ILT) is an important economic disease of the respiratory tract in chickens. The highly contagious disease is caused by Gallid alphaherpesvirus 1 (GaHV-1). This study aimed to investigate the effects of Newcastle disease vaccine on the laryngotracheitis vaccine. Therefore a total number of 125 twenty-seven days old LSL commercial pullet randomly divided into five groups and kept in the separate rooms at standard temperature. Then according to a special program, they were vaccinated with Newcastle disease and infectious laryngotracheitis vaccines. Three weeks after vaccination, the serums were tested by hemagglutination inhibition (HI) test for Newcastle disease and ELISA for infectious laryngotracheitis. The results of this study showed that the titer of infectious laryngotracheitis (1990 ± 631) in a group (G4) that received the Newcastle disease vaccine first and the infectious laryngotracheitis vaccine three days later was more significant than other groups (P > 0.05). Newcastle titer (5.1 ± 1.45) was non significantly lower in this group than in other groups. Also, Newcastle disease titer was non significantly higher in the group (G2) that first received the ILT vaccine (P > 0.05). The results of this study showed a positive effect of Newcastle disease vaccine if used before the laryngotracheitis vaccine. The results of this study showed that it is better not to use these two vaccines together and to get a higher titer, it is better to use a Newcastle vaccine before the laryngotracheitis vaccine. It is recommended that to study other live vaccines and their interactions.

کلیدواژه‌ها [English]

  • infectious laryngotracheitis
  • Newcastle
  • Vaccination
1- Awad, F., A. Forrester, M. Baylis, S. Lemiere, R. Jones, and  K. Ganapathy. 2015. Immune responses and interactions following simultaneous application of live Newcastle disease, infectious bronchitis and avian metapneumovirus vaccines in specific-pathogen-free chicks. Research in veterinary science 98: 127-133. 
2- De Boer, G., D. Van Roozelaar, R. Moormann, S. Jeurissen, J. Van Den Wijngaard, F. Hilbink and G. Koch. 1994. Interaction between chicken anaemia virus and live Newcastle disease vaccine. Avian Pathology 23: 263-275. 
3- Ebrahimi, M., S. Pourbakhsh, S.S. SHAH, R. Momayez and M. Gholami. 2003. Isolation Ans Identification Of Infectious Laryngotrachitis Virus From Commercial Flocks Of Iran Using Various Techniques. Archives of Razi Institute 56: 11-22. 
4- Ebrahimi , M., S. Shahsavandi , R. Mashhadi and A. Yousefi. 2020. Evaluation of immunization with infectious laryngotracheitis vaccine in White Bovans and HyLine W36 pullets. Veterinary Researches & Biological Products 32: 20-28.(In Farsi). 
5- Ellakany, H. F., A. R. Gado, A. R. Elbestawy, H. S. Abd El-Hamid, H. M. Hafez, M. E. Abd El-Hack, A. A. Swelum, A. Al-Owaimer and I. M. Saadeldin. 2018. Interaction between avian influenza subtype H9N2 and Newcastle disease virus vaccine strain (LaSota) in chickens. BMC veterinary research 14: 358.6- Ganapathy, K., P. Cargill, E. Montiel and R. Jones. 2005. Interaction between live avian pneumovirus and Newcastle disease virus vaccines in specific pathogen free chickens. Avian Pathology 34: 297-302. 
7- García, M. and S. Spatz. 2020. Infectious laryngotracheitis. pp.189-209. In: D. E. Swayne, M. Boulianne, C. M. Logue, L. R. McDougald, V. Nair, D, L. Suarez, S. de Wit, T. Grimes, D. Johnson, M. Kromm, T. Y. Prajitno, I. Rubinoff, G. Zavala (ed.). Diseases of poultry. John Wiley & Sons, Inc. New Jersey.
8- Geerligs, H. J., E. Ons, G. J. Boelm and D. Vancraeynest. 2015. Efficacy, safety, and interactions of a live infectious bursal disease virus vaccine for chickens based on strain IBD V877. Avian diseases 59: 114-121.
9- Fallah Mehrabadi, M. H., S. A. Ghafouri, A. Shoushtari, F. Tehrani, S. Masoudi, M. Abdoshah, S. Amir Hajloo and M. Shabani. 2020. Effectiveness of Thermostable Vaccine for Newcastle Disease Produced by the Razi Institute on Backyard Poultry in Iran during 2015. Archives of Razi Institute. 75: 1-7. 
10-  Haghighat-Jahromi, M., K. Asasi, H. Nili, H. Dadras and A. Shooshtari. 2008. Coinfection of avian influenza virus (H9N2 subtype) with infectious bronchitis live vaccine. Archives of virology 153: 651-655. 
11- Hanson, L., F. White and J. Alberts. 1956. Interference between Newcastle disease and infectious bronchitis viruses. American journal of veterinary research 17: 294-298.
12- Hidalgo, H. (2003). Infectious laryngotracheitis: a review. Brazilian Journal of Poultry Science 5: 157-168. 
13- Kaffashi, A., M. Mahmoudzadeh and S. Ataei Kachooei. 2021. Development of TaqMan Real-Time Polymerase Chain Reaction Assay for Detection of Chicken Anemia Virus in Newcastle Disease Vaccines. Archives of Razi Institute. 76: 421-427.
14- Menendez, K. R., M. García, S. Spatz and N. L. Tablante. 2014. Molecular epidemiology of infectious laryngotracheitis: a review. Avian Pathology 43: 108-117. 
15- Morrow, C. J and Whithear K. G. 2011. “Mycoplasma ts vaccines – 20 years field experience, pen trials and myths”. International Hatchery Practice. 25.5: 13-15.
16- Razmyar, J., S. Shokrpoor, A. Barin, J. Gheshlagh, P. Nakhaei, M. Khodayari, and S. M. Peighambari. 2021. Isolation of Infectious Laryngotracheitis Virus in broiler chicken in Iran: First Report. Veterinary Research Forum. 
17- Thornton, D. H. and J. Muskett. 1975. Effect of infectious bronchitis vaccination on the performance of live Newcastle disease vaccine. Veterinary Record 96: 467-468. 
18- Vagnozzi, A., M. García,  S. M. Riblet and G. Zavala. (2010). Protection induced by infectious laryngotracheitis virus vaccines alone and combined with Newcastle disease virus and/or infectious bronchitis virus vaccines. Avian diseases 54: 1210-1219. 
19- Van Leerdam, B.; Kuhne, P. 2009 Diagnosis of IBV Field Challenge—Poultry World. Available online at: https://www.poultryworld.net/Home/General/2010/7/Diagnosis-of-IBV-field-challenge-WP007714W/.  Accessed 10 January 2021.
19. World Organisation for Animal Health (OIE). OIE MANUAL OF DIAGNOSTIC TESTS AND 
VACCINES FOR TERRESTRIAL ANIMALS. 1: OIE; 2004.Newcaslte disease . p. 270-282.