بررسی غلظت سرمی کورتیزول و تأثیر سن، جنس و فصل بر روی آن در شتر یک کوهانه (Camelus dromedarius)

نوع مقاله: مقاله کامل

نویسندگان

1 مرکز تحقیقات بیماری‌های مشترک انسان و حیوان، دانشکده بهداشت، دانشگاه علوم پزشکی شهید صدوقی یزد،‌ یزد، ‌ایران

2 گروه علوم درمانگاهی، دانشکده دامپزشکی، دانشگاه شهید باهنر کرمان، کرمان، ایران

3 گروه مدیریت بهداشت دام، دانشکده دامپزشکی، دانشگاه شیراز ،شیراز، ایران

4 گروه علوم آزمایشگاهی، دانشکده پیراپزشکی، دانشگاه علوم پزشکی شهید صدوقی یزد، یزد، ‌ایران

چکیده

در این مطالعه تأثیرات فصل، جنس و سن بر روی غلظت سرمی کورتیزول و هم‌بستگی آن با سن دام‌ها در 180 شتر تک ‌کوهانه‌ی سالم (شامل 146 شتر نر و 34 شتر ماده) بررسی گردید. غلظت سرمی کورتیزول تفاوت معنی‌داری بین دو جنس نر و ماده نداشت و نیز هم‌بستگی معنی‌داری با سن دام‌ها نداشت. بین دو فصل تابستان و زمستان تفاوت نسبتاً معنی‌داری از نظر غلظت سرمی کورتیزول مشاهده گردید (06/0=p). در شترهای نر هم‌بستگی نسبتاً معنی‌داری بین سن با غلظت سرمی کورتیزول وجود داشت (08/0=p ،146/0-=r). هم‌چنین غلظت سرمی کورتیزول تفاوت معنی‌داری بین گروه‌های سنی مختلف شتر نداشت. در گروه سنی کمتر از پنج سال، غلظت کورتیزول سرم تفاوت معنی‌داری بین دو فصل تابستان و زمستان داشت (044/0>p). مطالعه‌ی حاضر نشان داد که فصل، جنس و سن می‌تواند بر تغییرات کورتیزول سرم در شتر تک‌کوهانه اثر داشته باشد و ممکن است علت نتایج متناقض گزارش شده در مطالعات قبلی درباره‌ی کورتیزول سرم در این‌ گونه باشد و باید در مطالعات بعدی در این ‌گونه مورد توجه قرار گیرد.

کلیدواژه‌ها


عنوان مقاله [English]

Evaluation of serum concentration of cortisol, and the effects of age, sex and season in dromedary camels (Camelus dromedarius)

نویسندگان [English]

  • A. Sazmand 1
  • J. Tajik (Late) 2
  • A. Rasooli 3
  • S.H. Hekmati Moghaddam 4
1 Zoonotic Diseases Research Center, School of Health, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
2 Department of Clinical Sciences, Faculty of Veterinary Medicine, Shahid Bahonar University, Kerman, Iran.
3 Department of Animal Health Management, School of Veterinary Medicine, Shiraz University, Shiraz, Iran.
4 Department of Laboratory Sciences, School of Paramedicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
چکیده [English]

In this study the effects of season, sex and age on serum concentration of cortisol, and its correlation with age in 180 clinically healthy dromedary camels (146 males and 34 females) were evaluated. Serum concentration of cortisol had no significant difference between two sexes, and had also no significant correlation with the age. There was a marginally significant difference between summer and winter seasons in serum cortisol (p=0.06). In male camels, there was a significant relationship between serum cortisol and the age (r=– 0.146, p=0.08). No significant differences were detected for the serum cortisol between different age groups of camels. In camels up to 5 years of age, the serum cortisol showed a significant difference between summer and winter seasons(p=0.044). The current study showed that season, sex and age may affect the changes of serum cortisol in dromedary camels, and can be proposed as the probable cause of controversial findings regarding serum cortisol in previous studies.

کلیدواژه‌ها [English]

  • Camel
  • Cortisol
  • Age
  • Sex
  • Season
1- Abdel-Fattah, M., Hashem, A., Azamel, A. and H. Farghaly. 2011. Effect of weaning stress, housing system and probiotics supplementation on cortisol, thyroid activity and productive performance of sucker camel calves. Journal of Radiation Research and Applied Sciences, 4(4B), 1291-1315.
2- Alila-Johansson, A., Eriksson, L., Soveri, T. and M-L., Laakso. 2003. Serum cortisol levels in goats exhibit seasonal but not daily rhythmicity. Chronobiology International, 20(1), 65-79.
3- Baraka, T. 2012. Clinical evaluation of vitamin A, ß-carotene, vitamin E and cortisol levels in health and selected diseases in camels (Camelus dromedarius) in Egypt. Journal of American Science, 8, 106-111.
4- Bengoumi, M., Faye, B., El-Kasmi, K. and F., De La Farge. 1997. Clinical enzymology in the dromedary camel (Camelus dromedarius). Part 2. Effect of season, age, sex, castration, lactation and pregnancy on serum AST, ALT, GGT, AP and LDH activities. Journal of Camel Practice and Research, 4(1), 25-29.
5- Berardinelli, J., Godfrey, R., Adair, R., Lunstra, D., Byerley, D., Cardenas, H. and R. Randel. 1992. Cortisol and prolactin concentrations during three different seasons in relocated Brahman and Hereford bulls. Theriogenology, 37(3), 641-654.
6- Bogin, E. 2000. Clinical pathology of camelids: present and future. Revue de Médecine Vétérinaire, 151(7), 563-568.
7- Bretschneider, G. 2005. Effects of age and method of castration on performance and stress response of beef male cattle: A review. Livestock Production Science, 97(2), 89-100.
8- Dahlborn, K., Benlamlih, S., Zine-Filali, R., Gueroulali, A., Hossaini-Hilali, J. and M. Oukessou. 1992. Food deprivation and refeeding in the camel (Camelus dromedarius). American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, 262(6), R1000-R1005.
9- Elias, E. and S. Weil. 1989. Serum cortisol levels in camels (Camelus dromedarius) during the reproductive cycle. Comparative Biochemistry and Physiology Part A: Physiology, 94(4), 787-790.
10- Flisińska-Bojanowska, A., Komosa, M. and J. Gill. 1991. Influence of pregnancy on diurnal and seasonal changes in cortisol, T3 and T4 levels in the mare blood serum. Comparative Biochemistry and Physiology Part A: Physiology, 98(1), 23-30.
11- Ghadrdan, A.R., Sazmand, A., Karimiyan, A. and S. Hekmatimoghaddam. 2013. Normal values and seasonal differences in the serum concentration of vitamin A and beta carotene in the Iranian camel (Camelus dromedarius). Iranian Journal of Veterinary Medicine, 7(2), 91-94.
12- Hekmatimoghaddam, S., Sazmand, A., Rasooli, A., Hamidinejat, H. and H. Jafari. 2012. Laboratory tests in dromedary camels naturally infected with piroplasms in Iran: study and review of literature. Journal of Camel Practice and Research, 19(2), 217-221.
13- Huber, S., Palme, R. and W. Arnold. 2003. Effects of season, sex, and sample collection on concentrations of fecal cortisol metabolites in red deer (Cervus elaphus). General and Comparative Endocrinology, 130, 48-54.
14- Kataria, N., Kataria, A., Agarwal, V., Garg, S., Sahni, M. and R. Singh. 2000. Effect of water restriction on serum aldosterone and cortisol in dromedary camel during winter and summer. Journal of Camel Practice and Research, 7(1), 1-7.
15- Majchrzak, Y.N., Mastromonaco, G.F., Korver, W. and G. Burness. 2015. Use of salivary cortisol to evaluate the influence of rides in dromedary camels. General and Comparative Endocrinology, 211, 123-130.
16- Misk, N., Youssef, H., Semiea, M. and A. El-Khabery. 1998. Radiographic studies on the development of teeth in camels. Journal of Camel Practice and Research, 5(1), 23-37.
17- Mohamed, H. 2006. Factors affecting cortisol status in camels (Camelus dromedarius). Journal of Animal and Veterinary Advances, 5(4), 307-309.
18- Nazifi, S., Gheisari, H. and H. Poorabbas. 1999. The influences of thermal stress on serum biochemical parameters of dromedary camels and their correlation with thyroid activity. Comparative Haematology International, 9, 49-53.
19- Okeudo, N. and B. Moss. 2005. Serum cortisol concentration in different sex-types and slaughter weights, and its relationship with meat quality and intramuscular fatty acid profile. Pakistan Journal of Nutrition, 4(2), 64-68.
20- Rasooli, A., Jalali, M.T., Nouri, M., Mohammadian, B. and F. Barati. 2010. Effects of chronic heat stress on testicular structures, serum testosterone and cortisol concentrations in developing lambs. Animal Reproduction Science, 117(1), 55-59.
21- Rasooli, A., Nour,i M., Khadjeh, G. and A. Rasekh. 2004. The influences of seasonal variations on thyroid activity and some biochemical parameters of cattle. Iranian Journal of Veterinary Research, 5(2), 1383-1391.
22- Saeb, M., Baghshani, H., Nazifi, S. and S. Saeb. 2010. Physiological response of dromedary camels to road transportation in relation to circulating levels of cortisol, thyroid hormones and some serum biochemical parameters. Tropical Animal Health and Production, 42(1), 55-63.
23- Sazmand, A., Rasooli, A., Nouri, M., Hamidinejat, H. and S. Hekmatimoghaddam. 2011. Serobiochemical alternations in subclinically affected dromedary camels with Trypanosoma evansi in Iran. Pakistan Veterinary Journal, 31(3), 223-226.
24- Tajik, J., Nazifi, S. and R. Eshtraki. 2016. The influence of transportation stress on serum cortisol, thyroid hormones, and some serum biochemical parameters in Iranian cashmere (Raini) goat. Veterinarski Archiv, 86(6), 795-804.
25- Tajik, J., Sazmand, A., Hekmatimoghaddam, S. and A. Rasooli. 2013. Serum concentrations of thyroid hormones, cholesterol and triglyceride, and their correlations together in clinically healthy camels (Camelus dromedarius): Effects of season, sex and age. Veterinary Research Forum, 4(4), 239-243.
26- Tajik, J., Sazmand, A., Hekmatimoghaddam, S., Rasooli, A. and Y. Mohammadzadeh. 2015. Serum concentrations of some ions in clinically healthy camels (Camelus dromedarius). Eurasian Journal of Veterinary Sciences, 31(4), 204-208.
27- Ur-Rahman, Z., Ahmad, N, Bukhari, S.A., Akhtar, N. and I. Haq. 2007. Serum hormonal, electrolytes and trace element profiles in the rutting and non-rutting one-humped male camel (Camelus dromedarius). Animal Reproduction Science, 101, 172-178.
28- Yadav, S. and U. Bissa. 1998. Factors affecting some blood constituents in camels: A review. Proceedings of the Third Annual Meeting for Animal Production Under Arid Conditions, 2, 32-48.