بیماری یون در ایران: مطالعه مروری نظام‌مند و فراتحلیلی (متاآنالیز)

نوع مقاله: مقاله مروری

نویسنده

فارغ‌التحصیل دکتری عمومی دامپزشکی از دانشکده‌ی دامپزشکی دانشگاه تهران

چکیده

اطلاعات موجود برای تصمیم‌گیری و اتخاذ سیاست‌های مناسب در جهت کنترل پاراتوبرکلوزیس در بسیاری از کشورهای جهان بر پایه‌ی اطلاعات منتشر شده از کشور‌های پیشرفته است. لذا این مطالعه با هدف تعیین وضعیت بیماری یون در ایران با روش متاآنالیز انجام شد تا با در اختیار گذاشتن اطلاعات جامع و دقیق مسیر را در جهت اجرای برنامه‌های موثر برای کنترل این بیماری هموار کند. این پژوهش یک مرور سیستماتیک بر اساس پایگاه‌های اطلاعاتی معتبر داخل و خارج کشور است. جستجو با کلید واژه‌های ایران، بیماری یون، گاو، گوسفند، بز، شتر، گاومیش، شیر و مایع سیمن وترکیبی ازآنها انجام گرفت. سپس تمام مقالات و پایان‌نامه‌های مرور شده که دارای معیار‌های ورود به مطالعه بودند مورد بررسی قرار گرفتند. داده‌ها با استفاده از روش متا‌آنالیز و نرم افزارComprehensive Meta Analysis نسخه 2 تحلیل شدند. شیوع ظاهری بیماری یون در جمعیت نشخوارکننده‌گان1/6% (5/8- 4/4: CI 95%) بود. همچنین میزان آلودگی شیر مخزن گله 3/28% (2/93- 1/1: CI 95%)، شیر انفرادی گاو 4/20% (2/30- 4/13: CI 95%)و میزان آلودگی مایع سیمن 4/11% (7/16- 6/7: %۹۵CI) بود. متاسفانه با وجود جمعیت بزرگ دامی در کشور و از طرفی آلودگی بالاتر بیماری یون در ایران نسبت به کشور‌های پیشرفته، تنها برنامه‌های رایج برای کنترل بیماری اختیاری و به عهده‌ی دامداران است. برنامه‌ی پایه در جهت کنترل بیماری یون، تشخیص دام‌های آلوده و حذف، مدیریت بهداشتی گله و واکسیناسیون است که اجرای این برنامه‌ها می‌تواند به کنترل هرچه کار‌آمدتر این بیماری در ایران می‌انجامد.

کلیدواژه‌ها


عنوان مقاله [English]

Johne's disease in Iran: A systematic review and meta-analysis

نویسنده [English]

  • Masoud Hassani
Graduated from the Faculty of Veterinary medicine, Tehran University, Iran.
چکیده [English]

Information available for decision-making and adoption of appropriate policies to control paratuberculosis in most countries is based on published data in developed countries. Therefore, this study aimed to determine the status of Johne's disease in Iran in a meta-analysis method to provide comprehensive and accurate information to implement effective programs to control the disease. This search is a systematic review based on authoritative databases inside and outside the country. The search was carried out by keywords of Iran, Johne's disease, cattle, sheep, goats, camels, buffaloes, milk, semen fluid, and their combination. Then all articles and theses that had necessary indexes were evaluated. The Data were analyzed using Comprehensive Meta-analysis software Version 2. The prevalence of Johne's disease in ruminants was 6.1% (95% CI: 4.4-8.5). In addition, the rate of infection for bulk tank milk, individual cow milk and semen fluid was 28.3% (95% CI: 1.1-93.2), 20.4% (95% CI: 13.4-30.2) and 11.4% (95% CI: 7.6-16.7), respectively. Unfortunately, despite the great population of ruminants in the country and the higher infection rate of paratubeculosis in Iran compared with developed countries, the current strategies for control of paratuberculosis are voluntary and considered by ranchers. Basic control strategies are management modification, testing, culling and vaccination, and implementation of these programs can be effective in control of the disease occurrence in Iran.

کلیدواژه‌ها [English]

  • Iran
  • Johne's disease
  • Meta-Analysis
  • Ruminants
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