Effects of intracerebroventricular injections of glucose and insulin on food intake in broiler cockerels

Editorial

Authors

1 Assistant Professor, Department of Physiology, Faculty of Veterinary Medicine, Tehran University, Tehran, Iran

2 Associate Professor, Department of Physiology, Faculty of Veterinary Medicine, Tehran University, Tehran, Iran

3 Veterinary Surgeon

Abstract

Glucose and insulin are two important factors in regulation of food intake. Also, existence of central glucoreceptors have been determined in human and many of  animal species, in this study the existence of central glucoreceptors and regulative role of glucose in ingestive behavior of broiler cockerels were studied. In this study used from 128 broiler cockerels. At the first, guide cannula implanted stereotaxicaly in right lateral ventricle of brains of chickens. At onset of experiments, birds were injected with different doses of glucose and insulin via intracerebroventricular. Then in other experiments, chickens received insulin prior to injection of glucose and cumulative food intake was measured 30, 60 90, 120, 150 and 180 minute after injections.The results of this study showed that glucose and insulin had no effect on food intake in chickens(p≥0.05). It is concluded that central glucoreceptors had no role in start of ingestive behavior in birds.

References

1 - باباپور، و و فرزانه سمیعی. 1376؛ اثرات مرکزی گلوکز، 2- د‌زوکسی- د‌- گلوکز و انسولین بر رفتار تغذیه ای خرگوش. مجله د‌انشکد‌ه د‌امپزشکی د‌انشگاه تهران ، جلد‌ 52(4 ): ص 11-1.##
2- Air, E.L., Benoit, S.C., Blake Smith, K.A., Clegg, D.J and Woods, S.C., (2002); Acute third ventricular administration of insulin decreases food intake, in two paradigms. Pharmacol Biochem Behav. 72(1-2): 423-9.##
3-  Andrews, K.M., Kelly, J., McGowan, M.K and Grossman, S.P., (1990); Effects of chronic intrahypothalamic infussion of insulin on food intake and diurnal meal patterning in the rat. Behavior Neurology. 104(2): 385.##
4- Booth, D.A., 1986; Effects of intrahypothalamic glucose injection on eating and drinking elicited by insulin. J Comp Physiol Psychol. 65: 13-16.##
5- Debons, A.F., Krimsky, I and from, A., (1970); A direct action of insulin on the hypothalamic satiety center. Am J Physiol. 219(4): 938-943.##
6- Delprete, E and Scharren, E., (1990);  Hepatic branch vagotomy attenuates the feeding response to 2-deoxy-D-glucose in rats. Exp Physiol. 75: 259-261.##
7- Lacy, M.P., Van Krey, H.P., Skewes, P.A and Denbow, D.M., (1985); Effect of intra hepatic glucose infusions on feeding in heavy and light breed chicks. Poult Sci. 64(4): 751-756.##
8-  Mayer, J., (1953); Glocostatic mechanism of regulation of food intake. New Engl J Med. 249: 13-16.##
9- Shimizu, H and Bray, G.A., (1990); Effects of insulin on hypothalamic monoamine metabolism. Brain Res. 510: 251-285.##
10- Shiraishi, J.I., Yanagita, K., Fujita, M and Bungo, T. (2007); Central insulin suppresses feeding behavior via melanocortins in chicks. Domest Anim Endocrinol. Abstract.##
11- Tajalli, S., Jonaidi, H., Abbasnejad, M and Denbow DM., (2006); Interaction between nociceptin‌/‌orphanin FQ (N‌/‌OFQ) and GABA in response to feeding. Physiol Behav. 89(3): 410- 413.##
12- Tsujii, S and Bray, G.A., 1990; Effects of glucose, 2DG, Phlorizin and insulin on food intake of lean and fatty rats. Am J Physiol. 258: 476-481.##
13- Wynne, K., Stanley, S., Mc Gown, B and Bloom, S., (2005); Appetite control. J Endocrinol. 184: 291-318.##

Files

History

  • Receive Date: 26 April 2015
  • Accept Date: 26 April 2015

Share

How to cite

Statistics