Evaluation of ethanolic extract of peganum Harmala on anxiety in mice

Document Type : Short Communication

Authors

1 Department of veterinary science, ,Islamic Azad University, Babol Branch, Bbol, Iran.

2 Department of Animal Science,,Qaemshahr branch, Islamic Azad University , Qaemshahr, Iran.

Abstract

e medicine complementary and medicine Herbal .system neural affect can and disorder common a as is Anxiety
 for proposed is Harmala peganum of effect benefit The .disorders anxiety with individuals among usage spread wide
 Harmala peganum of extract ethanolic of effect the study present the In . disease neurological variousin of treatment
 approximately weighing mice male 36 study experimental this In.mice male adult in evaluated was behavior anxiety on
 peganum of kg/mg 400 and 300 200, 100, ,diazepam ,control including groups treatments sex in studied were 35 to 30
 effect anxiolytic , treatment after minutes .30IP injected were extracts and Drug . extract alchoholic -hydro Harmala
 DUNCAN and ANOVA with analyzed were data Obtained .s 300 during Maz Plus Elevated was extract ethanolic of
 in presence of time the significantly increased dose kg/mg100 in extract ethanolic the that showed results The.Test
 anxiety shows which significantly ) OAE % (entries arms whole to entries arm open of ratio and )0/05‹p (arms Open
 mice in effect anxiolytic has dose kg/mg100 in Harmala peganum of extract ethanolic , results to According .reduction
.enzyme oxidase monoamine inhibit strongly that extract in present carbolines -Beta to related be may effect the a

Keywords

Main Subjects

References

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Veterinary Research & Biological Products
Volume 37, Issue 1
March 2024
Pages 27-33

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History

  • Receive Date: 18 March 2023
  • Revise Date: 01 July 2023
  • Accept Date: 01 July 2023

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