Evaluation of four common antibiotic classes in the muscle and liver of chickens slaughtered tehran by LC-MS/MS

Document Type : Full Research Paper

Authors

1 Food Hygiene Ph.D. Graduated, Department of Food Hygiene, Aytollah Amoli Branch, Islamic AZAD University, Amol, Iran.

2 Assistant Professor, Department of Food Hygiene , Aytollah Amoli Branch, Islamic AZAD University, Amol, Iran.

3 Professor, Department of Food Hygiene, Science and Research Branch, Islamic AZAD University, Tehran, Iran.

4 Assistant Professor, Department of Food Hygiene, Aytollah Amoli Branch, Islamic AZAD University, Amol, Iran

5 Associated Professor Department of Food Science and Technology, Aytollah Amoli Branch, Islamic AZAD University, Amol, Iran.

Abstract

Antibiotics are such compounds that are used for prevention or treatment during the breeding term. The lack of
attention of the farmers to veterinary recommendations regarding observance of the prohibition of slaughter and poultry consumption, increases the amount of residues in poultry meat. Regarding the complications caused of these
residues, such as drug resistance of germs, increased sensitivity to consumers, etc. In the present study, antibiotics
residues of different groups, including quinolones, macrolides and fluorophenicol were investigated. Totally 8 antibiotics
(4 antibiotical classes) in muscle and liver tissues of 90 samples from 13 slaughterhouses and 13 separate herds in early 1397 with a systematic random probability were collected, By liquid chromatography with a tandem mass spectrometer according the Grabnelli and el al method tested in the Residues Department of National Diagnostic Center of IVO.Finally, form 21 analytes that just Lincomycinthe macrolide class, and the enrofloxacin, ciprofloxacin in Quinolines was detected in sample and most of the frequency belong to ENR, LINCO.CIP, STZ respectively, and this ratio is
significantly correlated with both liver and chicken tissue matrix. It should be mentioned that in 24 and 16% of muscles and livers only one type of antibiotic was detected there aren’t any samples with more than one antibiotic. None of the positive amounts weren’t above ISIRI and EU MRLs, then again, the presence of antibiotics, in particular, can be a potential public health hazard.

Keywords


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