Evaluation of the correlation of beta hydroxyl butyrate with oxidative stress, energy and trace minerals parameters in dairy cows

Document Type : Full Research Paper

Authors

1 Depar. Internal Medicine and Clinical Pathology, Veterinary college, Urmia University, Urmia, Iran.

2 Associate Professor, Depar. Internal Medicine and Clinical Pathology, Veterinary college, Urmia University, Urmia, Iran.

3 Vet Graduated, Veterinary college, Urmia University, Urmia, Iran.

Abstract

The aim of this study was to investigate the relationship between beta hydroxyl butyrate (BHB) with glutathione peroxidase (GPX), triglycerides, cholesterol, glucose, copper, zinc and iron. Based on the reproduction condition, the 230 cows were classified into three groups of 7 to 9 months pregnant cows, 2 months calved cows and from 3 months to the dry period time. Based ob the serum BHB concentration, animals were divided into 4 groups of <0.08, 0.81-1.2, 1.21-1.39 and >1.4 mmol/l. Overall mean BHB was 0.64 mmol/l. BHB in cows calved to 2 months were significantly higher than in pregnant cows. The percentages of unhealthy cows was 17.4 including 10.4% with BHB 0.81-1.2, 2.6% with 1.21-1.39 and 4.4% with >1.4 mmol/l. Mean GPX and zinc was not differed among reproduction and BHB groups but triglyceride and cholesterol were differed. The lowest concentrations of copper, zinc and iron were in pregnant cows. Mean minerals among reproduction groups were significant for copper and iron but among BHB groups were not. BHB in pregnant cows were <0.8 mmol/l and were all health while in calved cows and up to dry period cows have had all types of BHB groups including clinical and subclinical ketosis. None of the blood parameters were significant in BHB >0.8 mmol/l. With the exception of glucose, BHB showed correlations with energy parameters in reproduction and BHB groups. BHB showed correlations with GPX and copper in 2 months cow’s calved and pregnant cows and with zinc in subclinical ketosis group. In conclusion, the subclinical ketosis was 4 folds of clinical ketosis. BHB concentration and energy parameters were depended on pregnancy and parturition positions, while GPX and trace minerals were not dependent. BHB with GPX and copper were correlated in reproduction groups. Finally, increase in serum BHB could accompany by low copper concentrations probably affects each other after post parturition in cows.

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References

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History

  • Receive Date: 30 October 2017
  • Revise Date: 23 April 2018
  • Accept Date: 01 May 2018

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