Prevalence of antibiotic resistance among bacterial pathogens isolated from dairy cows with mastitis in Far province

Document Type : Full Research Paper

Author

Assistant Professor, Razi Vaccine and Serum Research Institute, Shiraz Branch, Shiraz, Iran.

Abstract

Antibiotic resistance of bacterial agents of mastitis causes failure in treatment and spread of disease in herd and it can be considered as a threat for public health. Antibiotic resistance or susceptibility pattern is necessary to establish mastitis control program in an area. Milk samples from cows with clinical or subclinical mastitis were sent to bacteriological lab. The antibiotic resistance of isolated bacteria to gentamycin, ampicillin, penicillin, tetracycline, erythromycin and sulphamethoxazole/trimethoprim (SXT) were determined by disk diffusion method. Data were analyzed descriptively in the first step and then Chi-squared test was used to find seasonal and geographical differences. The most isolated bacteria were sensitive to gentamycin (80.42%) and SXT (73.43%) and resistant to penicillin (79.03%). Coagulase positive and negative Staphylococci were the most prevalent isolated bacteria. They had the highest sensitivity and resistance to gentamycin (92.31 and 88.24) and penicillin (80.77 and 58.72) respectively. Escherichia coli was resistant to penicillin in 88% of cases. Seasonal (except for SXT) and geographical differences were not observed. All over, our results demonstrated a wide range of antibiotic resistance in isolated bacteria from dairy cows with mastitis. It emphasized on the importance of rational and cautious use of antibiotics in the dairy farms of Fars province and establishing a regional plan for monitoring the resistance of antibiotics.

Keywords


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