The report of vaginal leiomyosarcoma in a dairy cow

Editorial

Authors

1 Department of Pathobiology, Faculty of Veterinary Medicine, Shahrekord University, Shahrekord, Iran

2 Department of Food Hygiene, Faculty of Veterinary Medicine, Shahrekord University, Shahrekord, Iran.

3 Expert of Pathobiology Department, Faculty of Veterinary Medicine, Shahrekord University, Shahrekord, Iran

Abstract

During rectal examination of a 5-year-old pregnant cow, a single multinodular vaginal mass was palpated and removed surgically after the parturition. Tissue samples of the mass were fixed in 10% neutral buffered formalin, paraffin-embedded, sectioned at 5 μm, and stained with hematoxylin – eosin and special stains.Grossly, the mass had two convex and flat surfaces. Multiple firm nodular masses and ulcers were observed in convex and flat surfaces, respectively. On cut section, the tumor was solid, nonencapsulated and gray-white with small yellowish foci. Histological examination of the mass revealed round to spindle cells with cellular and nuclear pleomorphism that arranged haphazardly. The tumor cells had indistinguishable cytoplasmic borders and prominent nucleoli. Necrotic debris and infiltration of inflammatory cells around bacterial colonies were seen in the tumor flat surface. There was diffuse fibrous connective tissue arranged in interwoven fascicles in different sections of the tumor too. According to macroscopic and microscopic features, the mass was diagnosed as vaginal leiomyosarcoma. To our knowledge, there is no report about occurrence of vaginal leiomyosarcoma in cow from Iran.

References

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Veterinary Research & Biological Products
Volume 24, Issue 3 - Serial Number 3
September 2011
Pages 42-47

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History

  • Receive Date: 22 April 2015
  • Accept Date: 22 April 2015

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